DANNY, real patient with DB

Healthy eyelids are essential for healthy eyes

DANNY, real patient with DB

Demodex blepharitis (DB) is an eyelid margin disease that can impact multiple ocular structures1,2

The eyelids and lashes work alongside structures like the lacrimal glands, cornea, conjunctiva, meibomian glands, and others to help maintain a healthy eye.3

Eyelids protect the ocular surface from trauma4

Eyelids provide a hydrated environment for optimal visual acuity4,5

Eyelashes form a barrier against debris and direct airflow away from the eye4,5

Compromised eyelids can increase
the risk of ocular surface disease

Due to their close relationship with other eye structures, eyelid health is an important consideration in overall eye care.

Common eyelid
disorders include6,7

  • Anterior blepharitis
  • Meibomian gland disease, also known as posterior blepharitis

Managing DB requires addressing the source

Inflammation caused by DB can affect more than just the eyelid, and Demodex mites can be a key driver of inflammation.1,6,8


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1. Fromstein SR, Harthan JS, Patel J, Opitz DL. Demodex blepharitis: clinical perspectives. Clin Optom (Auckl). 2018;10:57-63. 2. Rhee MK, Yeu E, Barnett M, et al. Demodex blepharitis: a comprehensive review of the disease, current management, and emerging therapies. Eye Contact Lens. 2023;49(8):311-318. 3. Schechter B, Mah F. Optimization of the ocular surface through treatment of ocular surface disease before ophthalmic surgery: a narrative review. Ophthalmol Ther. 2022;11(3):1001-1015. 4. Aumond S, Bitton E. The eyelash follicle features and anomalies: a narrative review. J Optom. 2018;11(4):211-222. 5. Carter SR. Eyelid disorders: diagnosis and management. Am Fam Physician. 1998;57(11):2695-2702. 6. Trattler W, Karpecki P, Rapoport Y, et al. The prevalence of Demodex blepharitis in US eye care clinic patients as determined by collarettes: a pathognomonic sign. Clin Ophthalmol. 2022;16:1153-1164. 7. Meibomian gland dysfunction and treatment. American Association for Pediatric Ophthalmology and Strabismus. Updated December 2020. Accessed October 9, 2025. https://aapos.org/glossary/meibomian-gland-dysfunction-and-treatment 8. Yeu E, Garg S, Ayres BD, et al. Current state and future perspectives in the diagnosis of eyelid margin disease: clinical review. J Cataract Refract Surg. 2024;50(8):868-875.